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Secondly, Since Jrme Boursiers study was conducted earlier, their definition of Ruminococcus may have differed from the current understanding

Predictive in vitro models A lack of robust and predictive in vitro models to assess the performance of these complex formulations remains a significant limitation

PLoS One 2014;9:e108210

A 2024 paper in Diabetes, Obesity and Metabolism found a similar small-molecule inhibitor dose-dependently limited body weight and fat mass gains, improved oral glucose tolerance and insulin sensitivity in obese mice [2]