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These include N-acetylaspartate, lactate, tryptophan, kynurenine, glutamate, creatine, linoleic acid, D-serine, glutathione, and 3-hydroxybutyrate, among others (72)

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Moreover, a post-hoc analysis of the STEP 1 trial confirmed the consistency of the semaglutide 2.4 mg weight-lowering potential regardless of baseline BMI 5%, 10%, 15% and 20% of body weight was 68.888.7%, 45.675.3%, 25.863.7%, and 13.139.6%, respectively (Fig