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The downstream effects most consistently described in the literature: induction of collagen I and III, elastin, and decorin synthesis (Maquart et al., FEBS Letters , 1988), upregulation of VEGF and basic FGF transcripts, induction of antioxidant defense genes including SOD2 and metallothionein isoforms, and modulation of the MMP-2 and TIMP-1/2 balance toward non-fibrotic remodeling

Vitamin B12 deficiency as a worldwide problem

I started out with a similar level (after a holiday in the south of France) but with a year plus of taking 2000iu d3 with 90mcg k2 daily it reached over 90

If the same vial were diluted with 4mL of water, the concentration would be halved to 2,500mcg/mL, and the same 2,500mcg dose would now require 1mL, or 100 units

It also helps with mood elevation and promotes anti-aging