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All animals were housed at room temperature under a 12/12 h light/dark cycle and had free access to food and water

ZhangLZhouJObianwunaUELongCQiuKZhangHet al

Numerous studies have identified many target genes of NRF2 and revealed functions of pleiotropic NRF2 in addition to its redox-regulating function

As the rate-limiting enzyme of the pentose phosphate pathway (PPP), glucose-6-phosphate dehydrogenase (G6PD) can promote the production of NADPH through increased activity, and together with PPP, it jointly participates in the regulation of glycolysis and redox balance