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It is widely available through licensed pharmaceutical suppliers and is the diluent most commonly specified in UK trial protocols and compounding guidance from the Specialist Pharmacy Service (SPS)

However, if you suspect deficiency or have risk factors, consult your GP rather than self-supplementing at high doses, as proper investigation of the underlying cause is essential for appropriate management

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Those with a faster metabolism or severe deficiency might notice the benefits waning more quickly, typically within one to two weeks, especially regarding the energy-boosting effects

SIRT1 activation also promotes fatty acid oxidation, reduces lipogenesis, improves insulin sensitivity, and enhances cellular stress resistance