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9 Acquired 5FU resistance is associated with increased mitochondrial content and signaling

You might consider a GSTM1 test if the results would change how you approach exposure reduction, antioxidant and glutathione support, or organ monitoring, particularly if you have significant environmental exposures or a family history of GST-related cancers or kidney disease

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Lugert S, Basak O, Knuckles P, Haussler U, Fabel K, Gotz M, et al

Association of p53 with neurodegeneration in Parkinson's disease