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Clarsen, B., Myklebust, G

Amongst the approved ICI agents, anti-PD1 agents have the largest indication across several tumours, including metastatic non-small cell lung cancer (NSCLC) [4], advanced head and neck cancer (HNC) [5], advanced melanoma [6], genitourinary tumours and others [7, 8]

M.McFarlandK.MelendezR

Nanoparticle formulationsincluding pHsensitive and PEGylated liposomes codelivering DON and gemcitabineenable targeted delivery and reduce offtarget toxicity

In addition to iron-catalyzed free radical chain reactions, lipoxygenase (LOXs) can directly oxidize PUFAs and lipid-containing PUFAs in cell membranes, which are considered to have an essential role in ferroptosis [75, 80]