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The 2024 Tsai split-face RCT in Journal of Cosmetic Dermatology demonstrated significant melasma severity reduction with combined microneedling radiofrequency plus cysteamine

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MC1R for tanning) and has been associated with increased libido and erectile function [1] [2] PT-141 (bremelanotide) a derivative of MT-II that works centrally rather than directly on vascular tissue BPC-157 a synthetic peptide with proposed tissue-healing properties, though it lacks human clinical evidence for ED and is not authorised for human use It is important to understand that none of these peptides are licensed by the Medicines and Healthcare products Regulatory Agency (MHRA) for erectile dysfunction and they are not recommended by NICE or the NHS for ED treatment

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