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Wyrembek P, Szczuraszek K, Majewska M, Mozrzymas JW (2010) Intermingled modulatory and neurotoxic effects of thimerosal and mercuric ions on electrophysiological responses to GABA and NMDA in hippocampal neurons

Absorption into the CNS after intranasal administration has been postulated to occur via the olfactory and trigeminal neuronal pathways (intraneuronal) and diffusion across mucosal barrier and olfactory plate (extraneuronal), depending on the size, polarity, and odorant nature

Reducing dehydroascorbic acid back to ascorbic acid is the opposite reaction

Dihexa acts through hepatocyte growth factor (HGF) and its receptor c-Met

To sum up, TCM shows its unique advantages in the management of epileptic comorbidities (mainly depression and cognitive impairment)