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Liposomes and lipid disks traverse the BBB and BBTB as intact forms as revealed by two-step Frster resonance energy transfer imaging

visible thickness changes typically take 1224 weeks

Journal of Inorganic Biochemistry

Of particular relevance to cancer cell therapy, LNPs surface-functionalized with antibody fragments targeting CD5 (a T-cell surface marker) and encapsulating CAR-encoding mRNA have enabled direct in vivo CAR gene modification of T cells, circumventing the need for complex ex vivo manufacturing (181)

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