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Increased acylcarnitine ratio indices in newborn screening for carnitine-acylcarnitine translocase deficiency shows increased sensitivity and reduced false-positivity

The human body needs various enzymes for the L-carnitine synthesis as well as the amino acids lysine and methionine, as well as iron, niacin, vitamin B6 and alpha-ketoglutarate

Metabolomics data can have a wide data distribution, and the experiments in Fig

Monitoring these side effects is essential, as they can vary significantly among individuals, necessitating a personalized approach to treatment

doi: 10.1016/j.heliyon.2024.e27724 227 van der ZaalB