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The capping group interacts with the amino acids at lysine binding site while the linker having the structural similarity to the carbon chain present in the acetyl-lysine substrate, connects the metal binding and capping group for interaction with the HDAC active site ( Figure 4 )

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[DOI] [PMC free article] [PubMed] [Google Scholar] 124.Frank D.N., St Amand A.L., Feldman R.A., Boedeker E.C., Harpaz N., Pace N.R

Above all, at very high concentrations, it coordinates programmed cell death in stressed plants [51]