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Reductive stress (RS), a condition characterized by an overcompensation in redox balance that favors reduction over oxidation, may be brought on by excessive or extended antioxidant use, according to mounting evidence

Briefly, TRPs are Ca 2+ -permeable channels known for their role in temperature sensation, but interestingly, have also been shown to play a role in the release of pro-inflammatory cytokines from microglia in mice exposed to immunogenic agents [i.e., lipopolysaccharide (LPS)] (Zhang Y

It is a tripeptidea small protein-like moleculemade from three amino acids: cysteine, glutamate, and glycine