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There are many reports that describe the in vitro production of endodermal cell types from hPSCs: thymic epithelial cells 26,27,28 , pancreatic beta cells 29 , lung epithelial cells 30 , intestinal cells 31 , cholangiocytes 32,33,34,35 and hepatocytes 3,5,6,11,36,37,38

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Compared to other B-cell malignancies, chronic lymphocytic leukemia (CLL) is not highly active metabolically (6)