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Yet, under regulation of the ISR pathway an ATF4-mediated upregulation of NRF2 via CHAC1 activity was shown as well (Kre et al., 2023), revealing a context-dependent interplay between CHAC1 and NRF2 that merits further study

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But maybe theyre already doing so and want a bigger mental rev-up, or maybe they want something easier than sweaty workouts and Russian novels: a pill

Cash A, Vernon SD, Rond C, Bateman L, Abbaszadeh S, Bell J, et al