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Longden said nicotine can be compared to caffeine

These alterations contribute to systemic inflammation by increasing the production of pro-inflammatory cytokines, including interleukin (IL)-1, IL-6, IL-8, IL-13, tumor necrosis factor-alpha (TNF-), and transforming growth factor-beta 1 (TGF-1) [24]

These include nicotine replacement therapy and certain medicines

To analyze the predictors of reducing cigarette consumption and quitting smoking, we performed a multivariable Generalized Linear Model with a log link (Poisson regression) and robust variance to obtain both crude (PR) and adjusted prevalence ratios (APRs) and their 95% CI

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