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Ethics statement The animal study was approved by the experimental protocol was approved by the Institutional Animal Care and Use Committee of Jining Medical University (Approval No

[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Chabon JJ et al

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2 Pathological characteristics and pathogenesis of blue light damage in the eyes 2.1 Pathophysiological characterization The pathways of blue light damage mainly include oxidative stress, endoplasmic reticulum stress and oxidative DNA damage, inflammatory response, mitochondrial damage and cell apoptosis, lysosomal autophagy and vascular endothelial damage ( According to morphological observations, blue light irradiation can cause congestion and edema of corneal limbal blood vessels, dilation and thinning of the central part of the cornea, protrusion forward, and increased curvature

As mentioned above, hyperglycemia can lead to endothelial dysfunction via various mechanisms