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Its most well-characterized mechanism involves stimulating collagen and glycosaminoglycan synthesis in skin fibroblasts, which underlies its effects on skin elasticity, firmness, and wound repair

When Se deficiency occurs in the context of already existing hypothyroidism, the symptoms of myxedema (such as puffiness of the skin, a hoarse voice, and slowness of mental function) may become more pronounced [73]

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The idea of intermittent fasting can be overwhelming, but youll be pleasantly surprised at how easy it is, especially compared to other types of eating plans

The other consistent context in the preclinical literature is a metabolic environment the mouse studies pair the compound with diet/energy-balance conditions rather than testing it in isolation