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171 GWAS in major populations consistently highlight urate transporter genes as pivotal loci influencing serum uric acid levels, 138,139 notably SLC2A9 (GLUT9) and SLC22A12 (URAT1), involved in urate reabsorption from urinary filtrates

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Natural Therapies For the purposes of this discussion, natural therapies include nutritional and herbal supplements as well as treatments from the field of complementary and alternative medicine (CAM), such as acupuncture or apheresis