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In addition, liver Kupffer cells rapidly removed 80% of RBC-derived vesicles from the circulation within 5 min, mainly via scavenger receptors [279]

This is by Vasireddi et al., so theres a bunch of different authors

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Then, we applied our previously proposed drug repositioning method which aims to repurpose useful drugs for targeting a specific gene based on the similarity analysis of the perturbations induced by the target gene knockdown and candidate drug treatment on the available human cell lines [13, 18]