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These experiments should aim to use human pancreatic endothelial cells from T1D donors and autoreactive CD8+ T cells to perform in vitro transwell-based extravasation assays

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Patients need to understand what the research suggests, what remains uncertain, and why symptoms such as chronic diarrhea, abdominal pain, blood in the stool, unexplained fatigue, rashes, food reactions, or suspected inflammatory bowel disease deserve proper evaluation

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