Without it, even the best brightening ingredients lose much of their effectiveness
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Four molecule families have peer-reviewed clinical evidence supporting their use in microinfusion-style delivery: copper tripeptide GHK-Cu (collagen synthesis, gene-expression modulation), recombinant epidermal growth factor or sh-Oligopeptide-1 (keratinocyte proliferation, dermal restructuring), polydeoxyribonucleotide PDRN (adenosine A2A receptor activation, fibroblast stimulation, anti-melanogenesis), and a multi-molecular-weight hyaluronic acid system (50 kDa to 2000 kDa fractions, each with different penetration depth and biological role)
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Morgan AS, Sanderson PE, Borch RF, Tew KD, Niktsu Y, Takayana T, VonHoff DD, Izbicka E, Mangold G, Paul C, Broberg U, Mannervik B, Henner DW and Kauvar LM
