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These results support the view that UA can delay aging by increasing the levels of SIRT1 and SIRT6

Completed Phase II and III clinical trials have indicated that the agent has a nonoverlapping toxicity profile and synergistic effects with carboplatin, paclitaxel, and anthracycline, has no cross-drug resistance and is well tolerated, with patients mostly reporting fatigue and nausea

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In one study, the effect of hexarelin on weight loss was examined in nonobese insulin-resistant MKR mice and their wild-type counterparts (FVB mice) over a period of 12 days