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Most people get enough vitamin B12 from their diet but certain groups make struggle to top up the nutrient this way, putting them at risk of a B12 deficiency
E-Posters - RECOVERY, REHABILITATION AND OUTCOME 03.00 - RECOVERY, REHABILITATION AND OUTCOME - 03.03 - PROGNOSIS AND OUTCOME AFTER STROKE P2312 - ESOC25-2352 MAPPING THE MODIFIED RANKIN SCALE (MRS) INTO THE 5-LEVEL EQ-5D (EQ-5D-5L) IN ISCHEMIC STROKE PATIENTS Florentina Pinckaers 1 , Janneke Grutters 2 , Silvia Evers 3 , Hester Lingsma 4 , Jeroen Boogaarts 5 , Diederik Dippel 6 , Linda Jacobi-Postma 1 , Aad van der Lugt 7 , Charles Majoie 8 , Yvo Roos 9 , Robert van Oostenbrugge 10 , Wim Van Zwam 1 , Andrea Gabrio 11 1 Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands, 2 Department for Health Evidence, Radboud UMC, Nijmegen, Netherlands, 3 Department of Health Services Research, Maastricht University, Centre of Economic Evaluation and Machine Learning, Trimbos Institute, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, Netherlands, 4 Department of Public Health, Erasmus MC University Medical Center, Rotterdam, Netherlands, 5 Department of Neurosurgery, Radboud UMC, Nijmegen, Netherlands, 6 Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands, 7 Department of Radiology, Erasmus MC University Medical Center, Rotterdam, Netherlands, 8 Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands, 9 Department of Neurology, Amsterdam UMC, Amsterdam, Netherlands, 10 Department of Neurology, Maastricht University Medical Centre+, Maastricht, Netherlands, 11 Department of Methodology and Statistics, Maastricht University, Maastricht, Netherlands Background and Aims: To translate the modified Rankin Score (mRS) at three months after ischemic stroke into EQ-5D-5L utility values, which may be used for the derivation of quality-adjusted life years for cost-effectiveness analyses
Palatable liquid can be added to feed or administered orally, no injections needed
The preservation of peptide stability has been observed for at least 28 days after reconstitution.[15] Peptides stored in BAC Water maintained 98% activity in assays up to 14 days post-reconstitution.[16] 2.3 Microbial Control & Aseptic Handling Benzyl alcohols bacteriostatic action has been well documented in pharmaceutical formulations, especially in multi-use vials, which ensures that peptides do not become contaminated during the study period.[17][18] Multiple use vials of BAC Water for research have shown reduced microbial load, even after repeated sampling.[19] 2.4 Storage & Stability Considerations While BAC Water extends the shelf life of reconstituted peptides, its effectiveness relies on proper storage conditions
Not intended for direct intravenous injection without proper medication reconstitution or dilution
