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These findings suggest that CCL7 may represent a candidate biomarker associated with IC/BPS and that CCR1 inhibition warrants further evaluation as a potential therapeutic target

Proc Natl Acad Sci USA 112:E5679E5688 Prasad S, Gupta SC, Tyagi AK (2017) Reactive oxygen species (ROS) and cancer: role of antioxidative nutraceuticals

The activity of catalase (CAT) and superoxide dismutase (SOD)-like enzymes is responsible for the effectiveness of these antioxidants, enabling them to neutralize destructive ROS (including H 2 O 2 , superoxide anions), giving them antioxidant effects ( Figure 5B )