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Clinical studies show that B12 injections have no major side effects, though rare cases of sensitivity may occur [20]

Several considerations are typically accounted for, besides accurate mass and RT, which includes the elimination of background signals, deisotoping, identification of adduct peaks in MS spectra, and MS/MS fragmentation patterns compared to databases or internal standards and the matching degree estimated (see Figure 2)

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doi: 10.1158/0008-5472.CAN-17-0240 104 SuryawanshiSHuangXElishaevEBudiuRAZhangLKimSet al

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