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B12 is water-soluble, meaning your body excretes what it doesn't need rather than storing it to potentially harmful levels

Curr Opin Pharmacol 7:355359 Mokhtari V, Afsharian P, Shahhoseini M, Kalantar SM, Moini A (2017) A review on various uses of N-acetyl cysteine

Some conditions that require precaution include: Diabetic Retinopathy: In clinical trials, it was observed that brand-name semaglutide can temporarily worsen eye problems in diabetic patients due to sudden hypoglycemia (drops in blood glucose levels), which can worsen diabetic retinopathy

Su et al., 2009

As part of shared decision-making, clinicians should counsel patients on all applicable options, with their risks and benefits