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Given the clinical significance of even small effect sizes associated with quitting [10], optimizing the use and efficacy of the nicotine patch is a pragmatic and feasible approach to the continuing problem of tobacco use disorder in the current, hard-to-treat population of smokers

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It uses a one-piece, multi-layer filter that combines four stages: a primary filter, high-efficiency activated carbon, a medium-efficiency filter, and a deodorizing cotton layer

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