doi: 10.3389/fonc.2025.1576781 Received 14 February 2025 Accepted 16 June 2025 Published 27 June 2025 Volume 15 - 2025 Edited by Sandip Patil, Shenzhen Childrens Hospital, China Reviewed by Francesco Grignani, University of Perugia, Italy Barbara A Osborne, University of Massachusetts Amherst, United States Katia Carneiro, Federal University of Rio de Janeiro, Brazil Madduri Srinivasarao, Purdue University, United States Updates Copyright 2025 Tian, Han, Song, Liu, Shen and Zhong
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Both variants had similar kinetic parameters as the WT, indicating that though catalytically unchanged, the stability of these variants is markedly reduced, with G6PD Plymouth present in even lower amounts and ultimately leading to more severe clinical manifestations
