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BPC-157 upregulates survival genes (Akt1, KRAS, Src, Foxo1), reduces inflammatory mediators (IL-6, TNF-, NOS2, NFB), scavenges reactive oxygen species through its four carboxylic groups, activates vascular bypass pathways, and maintains blood flow despite vessel occlusion
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(Curr Pharm Des, 2018) established that BPC-157's gastroprotective properties work through both systemic and local mechanisms, but achieving therapeutic blood levels requires careful consideration of delivery method