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Functions of GI-GPx: lessons from selenium-dependent expression and intracellular localization

Firstly, they used the double-click chemistry strategy to staple -helical peptides derived from the tumor suppressor p53 for the inhibition of p53-murine double minute 2 (MDM2) interaction and introduced cationic arginine (Arg) residues on the staple linkage to improve the cell permeability and activate capability of p53

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