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Studies have shown that IL-17A downregulates the expression of downstream target genes in the Wnt/-catenin signalling pathway, such as AXIN2 and CCND1, in osteoblasts and osteocytes, leading to bone loss by inhibiting the activity of osteoblasts and osteocytes

Oxidative stress occurs when there is an imbalance between free radicals and antioxidants in the body

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