Mast cells, which are abundant in the developing brain and highly responsive to bacterial antigens, likely contribute to the abrupt neuroimmune activation in these children
Additionally, while research is still emerging, there is some evidence to suggest that tranexamic acid may be beneficial in the prevention of UV-induced skin damage when applied topically
The cellular homeostasis between the GSH and GSSG ratio controls the cells redox level, maintained by reactions performed by glutathione reductases (GR) and glutathione peroxidases (GPX) (Mahmood et al., 2010)
Increased ROS by activated microglia (specialized macrophages of the CNS) during the immune response gives a state of increased lipid peroxidation, and the oligodendrocyte cell is the cell most susceptible to damage by ROS
A mixture of ultrapure water (0.6 mL) and chloroform (1.5 mL) was added to the above mixture for homogenization in the dark for 2 h, after which 4 mL of a chloroformmethanol mixture containing 0.01% BHT was added, shaken for 20 min, and the extract collected
