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This review will discuss the various therapeutic techniques being developed from each level of the central dogma with examples including: CRISPR activation (CRISPRa) and gene replacement at the DNA level, antisense oligonucleotides (ASOs) at the mRNA level, and small-molecule drugs at the protein level, followed by a review of current delivery methods for these therapeutics

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CryptandsConsisting of three chains connected by two nitrogen atoms, cryptands have a central cavity that can encapsulate a metal ion coordinated to the oxygen and nitrogen atoms

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