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General dysfunction would precede death, and it is loss of vital cuproprotein-based function in still living neurons that we argue is also key to AD

Finding the balance requires attention to technique

Additionally, funding agencies can also consider funding for degradation and toxicity studies that use high dimensional techniques such as siRNA seq, mass cytometry, and special transcriptomics to demonstrate single cell and tissue level toxicity of degradation products

Therefore, it may be wise to try different supplements and see how your body reacts as well as how you feel and how your overall health is over time

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