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Importantly, flow cytometric analysis of MZB both excluded any gene-dosage effect of Gclc expression and confirmed that loss of MZB was independent of any Cre -associated toxicity (Supplementary Fig

The administration of GSH, a precursor or a derivative, inhibits the replication both in vitro and in vivo

Conflict of interest The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

However, the ROS-detoxifying Nrf2 target genes, MnSOD and catalase, were eventually induced but with a significant delayed expression compared with the WT mice

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