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Mechanistic overlap: Both can influence metabolic pathways related to lipid mobilization and energy balance, though AOD-9604 is more targeted

Neisserial adhesin A (NadA) binds human Siglec-5 and Siglec-14 with high affinity and promotes bacterial adhesion/invasion

the alternative sigma factor E (E) that in pathogenic Neisseria species is activated in response to oxidative stress and negatively controls transcription of aniA , encoding the nitrite reductase ( The analysis of the genes involved in glutamate metabolism may provide a concrete example of how differences in gene regulation between meningococcal strains are directly associated with their pathogenic potential