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That said, its worth noting that the evidence supporting these uses is still limited, and more research is needed
B12 is necessary for digestion, protein synthesis, absorption of foods and the metabolism of fat and carbohydrates
You might also face difficulties getting the B12 you need if you have Celiac disease or Crohns disease, or if you are vegetarian or vegan
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History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy
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