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TB500 is thought to work throughout your whole body, not just in one spot

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[PMC free article: PMC370539] [PubMed: 3711337] 303

This deficiency specifically impairs mitochondrial Fe-S cluster proteins, leading to disruptions in electron transport chain activity, cellular energy metabolism, and cell cycle progression, ultimately resulting in growth inhibition and apoptosis

The Reward Prediction Error Mechanism Dopamine neurons respond most strongly not to rewards themselves, but to the difference between expected and actual outcomes