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Certain populations have slower or faster metabolisms due to genetic or environmental factors, impacting drug effects according to Role of Cytochrome P450 in Drug Metabolism by Guengerich, Pharmacology & Therapeutics, 2008

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Re: Topomatic--New Model (with handle) Posted by John Diamond on Saturday, 20-Oct-2007 First off thanks to all for the responses and apologies for not being able to respond

Alcohol creates pleasurable effects that reinforce repeated use, while nicotine causes dependency through its impact on brain chemistry

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