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The lack of sunlight, shorter days, and the tendency to stay indoors more often can all contribute to whats commonly known as the winter blues. One key factor that can significantly impact our physical and mental health during this time is the amount of essential vitamins were getting, especially Vitamin B12
Inhibiting NNMT with 5-Amino-1MQ restores NAD+ pools, which activates AMPK (AMP-activated protein kinase), the cellular energy sensor that shifts metabolism from glucose storage to fat oxidation
TB-500 is a synthetic version of the endogenous protein called thymosin beta-4, which is found in most human and animal cells
Some preclinical research has explored its potential role in supporting cognitive function, and one study referenced on the ReadyRx website investigated NAD+ supplementation in a mouse model of Alzheimer's disease with impaired DNA repair mechanisms, finding that NAD+ supplementation normalized several disease-related features in that animal model
References Hunt A, Harrington D, Robinson S (2014) Vitamin B12 deficiency
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