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The lack of smoke is a key selling point for IQOS and other heated tobacco products currently available on the market

However, one area you might not associate with smoking is your colon

We include the weighted average tax differential i.e., home state tax rate minus the weighted average border state tax rate between the home state and the bordering states to account for tax-induced shopping across state lines

Since they dont contain combustion byproducts (many of which are carcinogenic), e-cigarettes do offer an improvement over traditional cigarettes in this area

Mendez and Warner were optimistic that smoking prevalence would continue to fall on course, as it had in the early 2000s, but they concluded that major reductions, such as those presented in the Healthy People 2010 target, were unrealistic (Mendez and Warner 2004)