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It is frequently studied alongside BPC-157 because the two act through complementary tissue-repair pathways rather than the same one

Of note, a mediation analysis of STEP 13 trials performed by Wharton et al

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Higher scores indicated more severe degeneration [1]

Foundational Discovery Selective Senolytic Elimination in Aged Mice (Cell, 2017 Baar et al.) FOXO4-DRI Restores Fitness, Fur Density, Renal and Liver Function in Aged Mice The foundational study introducing FOXO4-DRI as a senolytic peptide was published in Cell by Baar and colleagues in 2017