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10.1126/sciadv.1701028 21 Serrano-LotinaA.PortelaR.BaezaP.Alcolea-RodriguezV.VillarroelM.vilaP

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Cardiovascular effects: Glucagon receptor agonism (via retatrutide) and GLP-1 receptor agonism have been associated with modest increases in heart rate as a class effect

rather, it underscores the necessity for more robust, high-quality, and standardized evidence to substantiate their routine application in clinical practice