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Astragalus polysaccharides (2-(Chloromethyl)-4-(4-Nitrophenyl)-1,3-Thiazole, APS) (As shown in Figure 2), a key active ingredient isolated from AM that contains over 200 constituents (Guo et al., 2019), has received a lot of attention over the past 2 decades

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Whilst some studies found beneficial effects in patients with AD 36 and dementia 90 and in shift workers, 91 others found no improvements in patients with sleepwake rhythm disorders