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Following euthanasia, the right kidney was fixed in 4% buffered formalin for a minimum of 24 h before further processing, while the left kidney was snap-frozen in liquid nitrogen and stored for subsequent analyses

10.1023/A:1015557300450 Plant Mol

Mechanistically, they activate Nrf2 and block ubiquitin-mediated GPX4 degradation, thereby inhibiting ferroptosis and alleviating cartilage erosion, pain, and gait abnormalities in DMM-induced OA (192)

Furthermore, bis-allylic carbon-containing PUFAs, such as the ones found in cardiolipin, may function as a filter in the inner membrane of the mitochondrial intermembrane space to trap deuterium before it reaches the ATPase pumps, protecting the cells from mitochondrial-respiratory chain dysfunction

Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as Doorstop for NADPH Entry