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Indeed, an argument has been made for considering only H 2 O 2 as the actual species involved among the ROS while NO and nitrosoglutathione (GSNO), a conjugate of NO and glutathione (GSH) that is produced by an as yet not definitively demonstrated oxidative mechanism, are responsible for ROS and RNS signaling

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KEY POINTS Riboflavin (Vitamin B2) is needed as a cofactor for several important enzymatic reactions in the body