Advancements in technology can help address challenges, such as standardizing parasite components, optimizing their delivery methods, and elucidating their mechanisms of action
Under basal conditions, Kelch-like ECH-associated protein 1 (Keap1) retains NRF2 in the cytoplasm, thereby preventing its nuclear translocation
Food Biosci 58:103685 Li M et al (2013) An ethnopharmacological investigation of medicinal Salvia plants (Lamiaceae) in China
1 Introduction Methotrexate (MTX) is a dihydrofolate reductase inhibitor and chemotherapeutic agent with proven efficiency against cancers and rheumatoid arthritis ( Oxidative stress, which results from the excess production of reactive oxygen species (ROS), has a fundamental role in the MTX-associated toxicities pathogenesis ( The endoplasmic reticulum (ER) is a fundamental cellular organelle responsible for the newly synthesized proteins folding into their final 3-dimentional structures, post-translational modification, transportation, and quality control ( Apoptosis is essential in cellular homeostasis maintenance and is activated during adverse conditions (Figure 1)
This plant is characterized by a rich phytochemical profile, encompassing alkaloids, phenolics, tannins, and saponins
