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While the simulations are confined by these assumptions, it is worth noting that redox cycling is governed by thermodynamics, which according to the reduction potential of doxorubicin, are favourable with respect to the formation of superoxide should a semiquinone radical species be present 3

This versatile compound is now actively investigated for its potential to combat age-related diseases, neurodegeneration, and to support human longevity 1 -4

Moreover, L-GSH in conjunction with RIF significantly increased TGF-1 levels compared to treatment with RIF alone

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