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The reasons for a link between vitamin B 12 deficiency and depression are not clear but may involve a shortage in S-adenosylmethionine (SAM)

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What you can upload A copy of your current prescription (PDF or photo) A medical record or chart note from your prescribing provider showing the active medication and dose A pharmacy printout or label from your most recent fill A recent lab result with your provider's name and the medication noted Existing RxPepsDirect patients on Sema or Tirz: we'll auto-match your email to your prior approved visit

Systemic lupus erythematosus (SLE) and rheumatoid arthritis have been noted in case reports